Chlamydia Swab Tests Explained: Accuracy, Pain, and Home Kit Options
Chlamydia and the Gut: A Secret Reservoir
Chlamydia (Chlamydia trachomatis) is a bacterium-based infection most often transmitted by vaginal, anal, or oral sex. While it primarily infects the genital areas, it may become established in the rectum or intestines—even among those who never had anal sex.
So how does it end up there? There are three principal ways:
Oral-fecal transmission: Chlamydia can be transferred from the genital to intestinal tract through bad hygiene or sex.
Vaginal-rectal transfer: Bacteria naturally shift from the vaginal tract to the rectum, especially in women.
Incomplete eradication: In some cases, antibiotics effectively remove chlamydia from the genital tract but are not effective in eradicating bacteria in the intestines.
A report in the journal Clinical Infectious Diseases found that people who are positive for rectal chlamydia might not have a history of anal sex, meaning that the bacteria can be present in the intestines without sexual contact
What is more worrying is that intestinal infections of chlamydia are asymptomatic, meaning that people can carry the bacteria for long periods of time without even realizing it.

How a Latent Chlamydia Infection Can Lead to Reinfections
Another of the largest problems with intestinal chlamydia is its ability to reinfect despite successful treatment.
Here's how it happens:
- A patient is diagnosed with genital chlamydia and treated with antibiotics.
- The genital infection resolves, but chlamydia bacteria remain hidden in the intestines.
- Eventually, the bacteria will re-colonize the genital tract, leading to a positive test.
This phenomenon, otherwise referred to as auto-reinfection, explains why others receive recurring chlamydia infection despite treatment and safe sex.
A study from the University of Maryland suggested chlamydia residing in the gut may have months or even years of being symptom-free during which time it can lie in wait. What this means is that an asymptomatic infection of the intestines could be behind unexplained repeated chlamydia diagnoses.
Check Your STD Status in Minutes
Test at Home with RemediumChlamydia Test Kit

Order Now $33.99 $49.00
Possible Dangers of an Untreated Intestinal Chlamydia Infection
While intestinal chlamydia is typically asymptomatic, it does not mean that it is harmless. If not treated, it can cause:
Chronic Reinfections
As mentioned earlier, intestinal chlamydia can be a reservoir, reinfecting the genital tract repeatedly. This increases the risk of chronic complications.
Risk of Pelvic Inflammatory Disease (PID)
For women, repeated chlamydia infections (even asymptomatic) can put them at risk for PID—a potentially life-threatening infection that can cause infertility, chronic pelvic pain, and ectopic pregnancy.
Increased Risk of Transmission
Chlamydia is very contagious, so people who unknowingly carry the bacteria in their guts will continue to pass it on to partners without even realizing it.
Impact on Gut Health
Although more study is needed, some scientists believe that repeated bouts of chlamydia infections in the digestive tract might disrupt balance of gut microbiome, which could have effects on digestion and immune systems【source】.

How to Detect and Treat Intestinal Chlamydia
Since intestinal chlamydia is not generally screened for, most doctors won't screen for it unless you request a rectal swab test. If you've experienced multiple episodes of chlamydia with no obvious reason, asking for a rectal test may be beneficial.
Methods of Diagnosis
- Rectal Swab Test: The simplest method of diagnosing intestinal chlamydia.
- Urine and Genital Swabs: Helpful in the case of genital chlamydia, but they won't detect hidden gut infections.
- NAAT (Nucleic Acid Amplification Test): A highly sensitive test that can detect chlamydia DNA in different parts of the body.
Treatment Options
Most chlamydia infections are treated with antibiotics like azithromycin or doxycycline, but some studies suggest that a longer or repeated course may be needed to fully eliminate gut-resident bacteria【source】.
If you’ve experienced recurrent chlamydia infections, talk to your doctor about whether additional or extended antibiotic treatment might be necessary.
Check Your STD Status in Minutes
Test at Home with RemediumChlamydia & Gonorrhea Test

Order Now $49.00 $98.00
For all 2 tests
Common Chlamydia and Gut Myths
Let's dispel some myths about this topic:
- Myth #1: Chlamydia infects only the genitals.
- Truth: Chlamydia infects the eyes, throat, rectum, and intestines—not just the genitals.
- Myth #2: You must have anal sex to get rectal chlamydia.
- Truth: The majority of individuals with rectal chlamydia have never engaged in anal sex. It can be spread through natural bacterial migration.
- Myth #3: Once you take antibiotics, chlamydia is gone forever.
- Truth: Most cases are treated successfully with antibiotics, yet latent infections in the intestines lead to reinfection.
- Myth #4: Chlamydia is always symptomatic.
- Truth: As many as 70% of infected people have no symptoms, so frequent screening is essential.
FAQs
1.- Can chlamydia actually live in the intestines?
Yes. Research has shown that Chlamydia trachomatis can persist in the gastrointestinal tract, often asymptomatic. It can remain undetected for years, which can lead to reinfections of the genital tract.
2.- How does chlamydia get into the intestines?
Chlamydia can get into the intestines by a number of different routes:
- Vaginal-to-rectal migration: In women, bacteria can migrate naturally from the vagina to the rectum.
- Oral-fecal transmission: Poor hygiene habits can transmit bacteria.
- Not completely eliminated: Antibiotics may rid the genital tract of infection but not eliminate gut bacteria.
3.- Can I reinfect with chlamydia from my own guts?
Yes. It is called auto-reinfection, when the chlamydia in the gut re-infecundate the genital area even after treatment. That's why some persons re-test positive after not engaging in sex after treatment.
4.- Do chlamydia infections of the intestine have symptoms?
Not usually. Unlike genital chlamydia, which may cause discharge or pain, intestinal chlamydia is not typically symptomatic. Some people have a bit of stomach discomfort, but this is not usual.
5.- Can I request an intestinal chlamydia test?
Yes, but most doctors don't automatically screen for rectal chlamydia unless there's a reason. If you've had repeated chlamydia infections, you should ask your doctor about a rectal swab test.
6.- How is chlamydia treated in the intestines?
The standard treatment for chlamydia is antibiotics like azithromycin or doxycycline. However, based on some studies, a longer or repeated course may be required to fully clear silent intestinal infections.
7.- If I've had chlamydia in the past, should I be worried about a silent infection?
If you've had recurrent infections despite treatment, intestinal chlamydia could be the culprit. Talking with a healthcare provider about further testing may be in order.
8.- Can intestinal chlamydia affect gut health?
While more research is needed, some scientists believe that recurrent chlamydia infections in the gut may disrupt the gut microbiome, which can impact digestion and immune function.
9.- How do I avoid chlamydia reinfections?
To decrease your risk:
- Get tested regularly, especially if you are sexually active.
- Use protection (dental dams and condoms) when having sex.
- Maintain good hygiene to prevent bacteria from spreading.
If infected, follow your treatment regimen carefully and ask about potential reinfection risk.
10.- Where can I learn more about chlamydia and preventing STDs?
For even more detailed info on chlamydia, STDs, and sex, check out our blog! We cover everything from symptom charts and testing methods to prevention tips.

What You Should Do Next
Now that you know that chlamydia is likely lying in wait in the intestines, reinfection and preventing STDs will work differently. If you have had chlamydia previously, testing and being absolutely certain that you're all treated is the key.
Get moving today:
- Discreet at-home STD test kits are the way to go.
- See a medical professional if you suspect a silent infection.
- Learn about STD prevention techniques to protect yourself and your partners.
- Check out our blog for professional sexual health guidance and testing details.
Early detection and treatment can prevent long-term effects. Be aware, get tested, and take control of your health!
Sources
1.- Chlamydia in the Gut: A Reservoir for Persistent Infection
2.- Chlamydia Can Settle in the Intestine
3.- Highly Viable Gastrointestinal Chlamydia trachomatis in Women
4.- Chlamydia Spreads to the Large Intestine Lumen via Multiple Pathways
5.- Chlamydia and Gut Microbiome: Understanding the Connection





