Sexually transmitted diseases (STDs) are some of the most common diseases worldwide. Some STDs such as syphilis have been around for centuries. Yet many misconceptions about STDs persist, owing to the stigma associated with such diseases and a lack of public discourse on the subject. Such misconceptions result in needless anxiety and may even lead to adverse consequences for one’s health. Here we address some of the most frequently asked questions about various STDs in a concise and easy-to- understand manner, covering a range of topics from the signs and symptoms of different STDs, to subjects such as STD testing, STD treatment, and transmission. Feel free to contact us if you have any questions that have not been addressed here.